Rare Pancreatic Cancer Patients May Live Longer When Treated With Radiation Therapy

Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy, according to a largest of its kind study in the November 15 issue of the International Journal of Radiation Oncology Biology Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

PNT is a very rare form of pancreatic cancer that can stay confined to the liver and often cause death from liver damage. Since it is usually unable to be removed by surgery, external beam radiation therapy (EBRT) is an attractive option for managing the disease, but the role of EBRT is largely unknown because of the low incidence of this tumor type and, as a result, very few related studies.

Researchers at the departments of radiation oncology and internal medicine, division of hematology/oncology and comprehensive cancer center biostatistics unit at the University of Michigan in Ann Arbor, Mich., sought to determine if PNTs are not as resistant to radiation therapy as was previously thought.

source: ASTRO