Friday, January 11, 2008

Phoenix Definition Of Biochemical Failure Predicts For Overall Survival In Patients With Prostate Cancer

UroToday.com- The Phoenix definition of prostate cancer biochemical failure (BF) following radiotherapy (XRT) is a more robust determinant of patient outcome compared with the ASTRO definition according to a report in the online version of Cancer, by Dr. Abramowitz and colleagues.

The ASTRO definition of BF is 3 consecutive rises in the PSA after the post-treatment PSA nadir backdated to the midpoint between the nadir and the first rise. The Phoenix definition is the nadir PSA + 2. The present study compared the two definitions as determinants of distant metastasis (DM), cause-specific mortality (CSM), and overall mortality (OM).

MedicalNewsToday

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